I am very geeked about the this announcement:
“In research published in the May 22 issue of the journal Biochemistry, the researchers say that with the addition of the recreated gene, PfMDR1 and its protein, they have all the biomolecular tools necessary to molecularly understand how the malarial parasite Plasmodium falciparum (P. falciparum), has become resistant to most of the drugs that could once destroy it. They have already described and expressed two other genes known to confer drug resistance.”
While drug resistance to regular malarial treatments is about the only thing the junkscience/ProDDT/Rachel carson is evil folks haven’t denied, it is an important part of the malarial control puzzle.
There is a very nice brief discussion of how malaria manipulates the proteins on its cell membrane to fool our immune system at Aetiology‘s blog, and she covers how that can translate into resistance.