I am very geeked about the this announcement:

“In research published in the May 22 issue of the journal Biochemistry, the researchers say that with the addition of the recreated gene, PfMDR1 and its protein, they have all the biomolecular tools necessary to molecularly understand how the malarial parasite Plasmodium falciparum (P. falciparum), has become resistant to most of the drugs that could once destroy it. They have already described and expressed two other genes known to confer drug resistance.”

While drug resistance to regular malarial treatments is about the only thing the junkscience/ProDDT/Rachel carson is evil folks haven’t denied, it is an important part of the malarial control puzzle.

There is a very nice brief discussion of how malaria manipulates the proteins on its cell membrane to fool our immune system at Aetiology‘s blog, and she covers how that can translate into resistance.

Posted by Gwen Pearson

Writer. Nerd. Insect Evangelist. Have you heard the good news? BUGS!

One Comment

  1. “While drug resistance to regular malarial treatments is about the only thing the jjunkscience/ProDDT/Rachel carson is evil folks haven’t denied, it is an important part of the malarial control puzzle.”

    Sometimes one need not deny something outright. Merely ignoring the reality of something (acting as if it did not exist) is usually sufficient when acknowledgment would cast doubt on the truth of one’s claims.

    Some have clearly chosen the “ignoring” option with regard to the development of resistance to DDT in mosquitoes and the impact of this on the resurgence of malaria in some areas.

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