Did you know that some insects are Regulated as Medical Devices? Yep. Maggot Therapy.

I’ve mentioned it a few times before at the Bug Blog, and in these days of MRSA bacteria, diabetic ulcers, and a whole host of other nasties, this ancient way of cleaning wounds is making a comeback.

Maggots are used in wound debridement–which is a fancy way of saying that when a wound is seriously infected, tissue begins to die (become “necrotic”) and has to be removed.  When doctors debride with scalpels, a lot of healthy tissue can be lost, and it leaves a big hole behind. It is not pretty.

This is why I am choosing to link to photos, and let you decide just how curious you are about this entire topic before you click.

While the idea of maggots on open wounds gives some the squicks, the results are amazing. It’s basically microsurgery by thousands of tiny crawling doctors.  Um, tiny crawling doctors who eat decaying tissue.

When antibiotics fail, or ulcers develop, or the patient’s immune system just isn’t able to cope– that’s when maggots get the call to save the day.

Medicinal maggots have several beneficial effects on wounds: debridement, (removal of necrotic tissue) is a primary use.  Left untreated, gangrene and amputation are the usual result for wounds that have become septic.  This may help explain why patients are willing to spend several days pretending that there are not thousands of tiny legless animals crawling around in their body, eating their flesh.

Maggots also produce a variety of salivary proteins that actually disinfect the wound through microbial killing. These secretions also seem to actually decrease wound healing time.  (Out of curiosity, please report back how many times you experience intrusive thoughts about the healing properties of maggot saliva today.)

You can see some before/during/after maggot treatment photos in this journal article.  The results of the maggots are astonishing– I would not have predicted the first patient’s hand could have been saved at all, much less partially reconstructed.

There are a fair number of interesting online videos–you can see the doctors, patients, and maggots at work:

There is a more disturbing video here, mostly because they use time-lapse video of maggots in their natural habitat–decomposing corpses.  You don’t use just any old maggots for this type of wound treatment; only a few species have the proper behaviors and will stop at eating just the decaying bits of you.  Also, medicinal maggots must be reared under sterile conditions so they don’t introduce any new infections to the one they are trying to cure.

Ronald Sherman has really pioneered maggot therapy in the last 20 years, and you can read his book online via Google books.  He also publishes peer-reviewed research regularly, and runs a company that supplies sterile maggots for medical use.  He is the lead author on a very nice review article about medicinal maggots in general, which I have linked below.

And, he has a clinical case page. Click at your own risk!

Some references about medicinal use of maggots:ResearchBlogging.org

Sherman, R. (2003). Maggot Therapy for Treating Diabetic Foot Ulcers Unresponsive to Conventional Therapy Diabetes Care, 26 (2), 446-451 DOI: 10.2337/diacare.26.2.446

Sherman, R., Hall, M., & Thomas, S. (2000). Medicinal Maggots: An Ancient Remedy for Some Contemporary Afflictions Annual Review of Entomology, 45 (1), 55-81 DOI: 10.1146/annurev.ento.45.1.55

Jukema, G., Menon, A., Bernards, A., Steenvoorde, P., Rastegar, A., & van Dissel, J. (2002). Amputation‐Sparing Treatment by Nature: “Surgical” Maggots Revisited Clinical Infectious Diseases, 35 (12), 1566-1571 DOI: 10.1086/344904

LayScience covered the first reports in peer reviewed journals of Maggot Therapy as reported during WWI.

Posted by Gwen Pearson

Entomologist. Educator. Writer. NERD.


  1. So cool. I used to gag seeing this the first time, but now, call me fascinated.

  2. Ew. But fascinating. Thanks for posting this- it’s good to see you blogging back up to speed.

  3. EW!

    I’m not sure which sentiment overrides the other…

  4. If all the dead tissue is consumed and the maggots are still hungry , will they eat the living tissue. If not why?

  5. My friends brother got a nasty puncture injury to his knee, which for complicated reasons did not get treated by a doctor for several days. By the time he saw a doctor the wound already had some wiggly new inhabitants, which a hospital nurse later told him had probably saved his leg.

    And yes, I think I will be having intrusive thoughts about this subject for the rest of the day now; thank you!

  6. Science overload for the day. Blech.

  7. John–your question gets at the heart of why only some maggot species are appropriate for this kind of therapy.

    The species commonly used are only interested in dead tissue. If they run out of nastly stuff to eat, they will simply migrate off the patient. They won’t begin to eat healthy tissue. This stems from the flies habits in the wild–they normally eat carrion.

  8. >They won’t begin to eat healthy tissue

    I am so, so relieved to hear that :-)

  9. […] fly (Lucilia sericata) Bug Girl discusses the resurging use of bottle fly larvae in her post, Maggot therapy.  The academic among us will appreciate her discussion of the mechanisms that allow these […]

  10. It just goes to show that Mother Nature knows best….fascinating and yucky all at the same time..Michelle

    Autumn Meadowhawks Mating.

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