Bedbugs and Pesticide Resistance

I discovered that bed bug evolution–specifically resistance to pesticides–was also the subject of the National Evolutionary Synthesis Center‘s podcast this month.  A FASCINATING interview with one of the grand old men of evolutionary genetics, James Crow.  He worked on DDT resistance back in the late 40s and 50s.

There is also a wonderful accompanying article at Understanding Evolution.  And, they repeat something that I’ve tried to explain in the past:

“Like pyrethrums, DDT kills insects by acting on the sodium pores in their nerve cells — and it just so happens that many of the same mutations that protect an insect against DDT also happen to protect it from pyrethrums. When DDT was first introduced, such mutations were probably extremely rare. However, with the widespread use of DDT in the 1950s and 60s, such mutations became much more common among bed bugs through the process of natural selection. Though DDT is rarely used today because of its environmental effects, these mutations have stuck around and are still present in modern bed bug populations. Because of the action of natural selection in the past (favoring resistance to DDT), many bed bug populations today are primed with the right sort of genetic variation to evolve resistance to pyrethrums rapidly.”